Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

Original Research

RMJ. 2018; 43(4): 623-626


Pattern of Hemoglobinopathies on HPLC among patients referred to selected centers in Peshawar, Pakistan

Khalid Khan, Saiqa Zahoor.

Abstract
Objective: To find the pattern of hemoglobin disorders and variants in patients referred to selected diagnostic centers in Peshawar.
Methodology: This study was performed on patients referred for hemoglobin electrophoresis from June 2016 to June 2017 at Khalid laboratory and Rehman Medical Institute, Peshawar. A detail history, general physical examination and history of blood transfusion were recorded. Results: Out of 809 subjects, 326(40.30%) were found to have some form of Hemoglobin disorders. Out of the 326 cases, Thalassemia trait were found in 256(78.5%), HbE Trait 5(1.5%), HbE disease 3 (0.9%), HbD disease 1(0.3%), HbD trait 6 (1.8%), Sickle cell trait 4(1.3%), Sickle cell Beta thalassemia 6(1.8%), Sickle cell disease 5(1.5%), Hereditary persistence of fetal hemoglobin 4(1.3%) and thalassemia major in 36(11.0%).
Conclusion: Hemoglobin disorders are quite common in our community. It is responsible for severe socioeconomic problems in the affected families. Prevention especially by premarriage screening may help in controlling these diseases.

Key words: Electrophoretic pattern, Hemoglobin disorders, HPLC



Share this Article


Advertisement
Oxidants and Antioxidants in Medical Science

SUBMIT YOUR ARTICLE NOW


ScopeMed.com
BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.