Results of this study showed that the combined use of Staph. aureus vaccine and extended intramuscular antibacterial therapy have a relatively high probability of curing and eliminating Staph. aureus mastitis in dairy cows through enhancing the animalís immune status and stimulating strong humoral immune responses in blood and milk. As raising antibodies leads to increasing opsonic capacity with antibacterial treatment to improve bacteriological clearance of infection.
Key words: Mastitis, Staphylococcus aureus, Vaccine, Treatment.