Objective: To determine the frequency of sore throat in patients undergoing intubation as part of general anesthesia using intravenous dexamethasone and lidocaine before endotracheal intubation.
Methodology: In this randomized controlled trial, total of 200 patients equally divided into two groups were selected. Group A was given inj dexamethasone 8mg i/v and Group B was given inj lidocaine 1mg/kg body weight i/v. Mean ages in both the groups were 40.20+13.12 and 47.21+10.68, respectively. Patients with sore throat were mild 25(25%), moderate 28(28%) and severe 12(12%) in dexamethasone group and mild 25(25%), moderate 28(28%), severe 14(14%) in lidocaine group. Patients with no sore throat in Group A were 35(35%) and patients in Group B with no sore throat were 33(33%). We considered mild sore throat as no sore throat, this complaint is only by asking the patient according to scoring of sore throat. Chi-square test was used to compare the frequency of sore throat between two groups.
Results: The frequency and severity of sore throat in Group A (dexamethasone) was 40% and Group B (Lidocaine) was 42% (p=0.998).
Conclusion: Dexamethasone and lidocaine before endotracheal intubation reduced the frequency and severity of postoperative sore throat in patients receiving general anesthesia with endotracheal intubation. However, the difference was not statistically significant.
Key Words: Sore throat, endotracheal intubation, dexamethasone, lidocaine