Home|Journals|Articles by Year Follow on Twitter

Directory for Medical Articles
 

Open Access

Case Report

J Pak Dent Assoc. 2018; 27(3): 152-156


POLYMORPHOUS ADENOCARCINOMA (PAC)

Humayun Kaleem Siddiqui, Ausaf Ahmed Khan, Sharjeel Bashir, Syed Muratza Raza Kazmi.

Abstract
Introduction: Polymorphous adenocarcinoma (PAC) is almost entirely related to minor
salivary glands. Mostly found in the palatal region but on rare it was also observed in other
intraoral areas. Histopathologically Polymorphous adenocarcinoma is non-encapsulated and shows infiltrative borders. Morphologically there are different growth patterns responsible for difficulty in diagnosis and confusion with other salivary gland tumours. In recent studies it is observe that there is a potential for histological transformation of the lesion from low to high grade malignancy.

Case Report: A 52 year old male reported to Memon Medical Institute Hospital dental OPD with growth on hard plate for 6 months and mobility of teeth. The lesion was painless with no signs of ocular involvement. Lesion was extending from premaxillary region covering whole of the hard palate to soft palate and beyond. CT scan shows heterogenous enhancing mass with calcifications probably arising from alveolar process of left upper jaw causing complete destruction of left alveolar processes with maxillary bone and hard palate. A plan for total maxillectomy discussed with the patient and the defect will be filled with a hollow acrylic obturator.
Discussion: Polymorphous Adenocarcinoma (PAC) is an uncommon tumour and mostly related to minor salivary glands. We describe here a case report of PAC arising from minor salivary glands of the palate. Our case showed different radiographic features that was resembled to slow growing tumour but aggressive in nature. In most of cases excision with wide margin is recommended, but in some cases modified radical neck dissection is indicated. Recurrences may occur after a long period, so for prevention prolonged follow up is recommended.
Key words: Adenocarcinoma, Palate, Salivary glands, Tumour.

Key words: PAC, Adenocarcinoma, Palate, Salivary glands, Tumour



Similar Articles

The Hob proteins are novel and conserved lipid-binding proteins at ER-PM contact sites.
Neuman SD, Jorgensen JR, Cavanagh AT, Smyth JT, Selegue JE, Emr SD, Bashirullah A
Journal of cell science. 2022; 135(5):

GLP-1 based therapies and disease course of inflammatory bowel disease.
Villumsen M, Schelde AB, Jimenez-Solem E, Jess T, Allin KH
EClinicalMedicine. 2021; 37(): 100979

Lipidomic analysis of meibomian glands from type-1 diabetes mouse model and preliminary studies of potential mechanism.
Wang H, Zhou Q, Wan L, Guo M, Chen C, Xue J, Yang L, Xie L
Experimental eye research. 2021; (): 108710

Molecular characterisation of sporadic endolymphatic sac tumours and comparison to von Hippel-Lindau disease-related tumours.
Schweizer L, Thierfelder F, Thomas C, Soschinski P, Kim HY, Jödicke R, Woltering N, Förster A, Teichmann D, Siewert C, Klein K, Schmid S, Nunninger M, Thomale UW, Onken J, Mühleisen H, Schittenhelm J, Tatagiba M, von Deimling A, Reuss DE, Solomon DA, Heppner FL, Koch A, Hartmann C, Staszewski O, Capper D
Neuropathology and applied neurobiology. 2021; ():

Transcription start site-level expression of thyroid transcription factor 1 isoforms in lung adenocarcinoma and its clinicopathological significance.
Sano K, Hayashi T, Suehara Y, Hosoya M, Takamochi K, Kohsaka S, Kishikawa S, Kishi M, Saito S, Takahashi F, Kaneko K, Suzuki K, Yao T, Ishijima M, Saito T
The journal of pathology. Clinical research. 2021; ():


Full-text options


Latest Statistics about COVID-19
• pubstat.org


Add your Article(s) to Indexes
• citeindex.org






Covid-19 Trends and Statistics
ScopeMed.com
CiteIndex.org
CancerLine
FoodsLine
PhytoMedline
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.



ScopeMed Web Sites