Home|Journals|Articles by Year|Audio Abstracts
 

Original Article



Yellow Mangifera indica Linn. and Artocarpus heterophyllus Lam. seed starch as binder and disintegrant in paracetamol tablet formulation

Richelle Ann Mallapre Manalo, Erna Custodio Arollado, Joriza Mae Monterola Pellazar, Mae Pauline Facistol Siocson, Romeo-Luis Frias Ramirez.




Abstract

Utilization of fruit by-products offers a potential solution in minimizing the economic and environmental problem posed by these wastes. In this study, the seeds of yellow Mangifera indica Linn. and Artocarpus heterophyllus Lam. were used as sources of starch as binder and disintegrant in the formulation of paracetamol tablet. Physicochemical, binder and disintegrant properties of the isolated starches were measured and evaluated based on the United States Pharmacopeia (USP) specifications. The M. indica and A. heterophyllus seed starches were white to off-white in color, odorless, has fine texture and yielded 25.64% and 44.85% starch, respectively. The M. indica seed starch has elongated-shaped while A. heterophyllus has smaller polygonal granules, resulting in passable to poor flowability. The lower solubility (p=0.004), and higher swelling power (p

Key words: Yellow mango, jackfruit, seeds, binder, disintegrant, paracetamol






Full-text options


Share this Article


Online Article Submission
• ejmanager.com




ejPort - eJManager.com
Refer & Earn
JournalList
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.