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Original Article



Hematological Changes in Albino Rats Following Subacute Exposure to Viva Plus Detergent: Implications for Household Chemical Safety

Aliyu Yahaya Gwiokura,Umar Abdullahi Maina,Emmanuel Oluwasegun Adawaren.



Abstract
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Background: The ubiquity of household detergents raises concerns about their potential hematotoxic effects, particularly in populations vulnerable to accidental exposure.
Methods: This investigation examined the hematological consequences of subacute oral administration of Viva Plus detergent in albino rats across three dose tiers (n=5/group: Grp A;1000, Grp B; 2000, and Grp C; 5000 mg/kg bw/day) over a 14-day period starting from 8th to 24nd of July 2025.
Results: The hematological profiling revealed a striking dose-response relationship: leukocyte counts increased progressively from 8.2 ± 1.1 ×10³/μL in controls to 17.9 ×10³/μL at the highest treatment dose (p

Key words: RRed blood cells (RBCs), Hematotoxicity, Detergent exposure, Viva Plus, Albino rats, Hematology







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