Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

Original Research

AAM. 2017; 6(3): 90-97


Evaluation of Larvicidal Activity of Bakuchi (Psoralea corylifolia Linn.) Beeja Extracts Against Aedes aegypti Larvae

Supreeta Laxmanshetty, DG Kolume.

Abstract
Mosquitoes transmit numerous diseases such as malaria, chikungunya, dengue fever, and yellow fever. Indiscriminate use of synthetic insecticides to eradicate mosquitoes nowadays steered to diminution in physiological resistance, which has led to investigate a safe and environment friendly alternative. In the current investigation, bakuchi (Psoralea corylifolia Linn.), an ayurvedic drug having krimighna (act against worms) action, was evaluated for larvicidal bioefficacy against Aedes aegypti larvae. Hence, the study was attempted to evaluate the larvicidal bioefficacy of petroleum ether, ethanol, and aqueous extracts of bakuchi beeja against Aedes aegypti larvae. Petroleum ether, ethanol, and aqueous extracts of bakuchi were collected by soxhlet extraction and cold maceration, respectively. The extracts were evaluated for the larvicidal activity. The larvicidal bioassay was performed by following WHO (2005) guidelines with slight modification and the mortality was recorded after 24 h. The obtained mortality data were subjected to log-probit analysis to determine
the median lethal concentrationsóLC50 and LC90. Aqueous extract exhibited LC50 at 699.915 ppm, LC90 at 971.635 ppm; ethanolic extract exhibited LC50 at 66.71 ppm, LC90 at 127.80 ppm; and petroleum ether extract exhibited LC50 at 25.8 ppm and LC90 at 61.0 ppm against late third and early fourth instar Aedes aegypti larvae. From the results obtained, it was revealed that among the three extracts of bakuchi, petroleum ether extract exhibited higher mortality at a lower dose when compared to ethanol and aqueous extract. Hence, the study reasonably concludes that bakuchi carry potential as a mosquito larvicide and could be explored for the development of safer larvicide.

Key words: Aedes aegypti, bakuchi (Psoralea corylifolia Linn.), larvicidal activity



Share this Article


Advertisement
Journal of Interdisciplinary Histopathology

SUBMIT YOUR ARTICLE NOW


ScopeMed.com
BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright © ScopeMedģ Information Services.