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Original Article

J App Pharm Sci. 2017; 7(10): 168-181

Ameliorative Effect of Carob Pods Extract (Ceratonia siliqua L.) against Cyclophosphamide Induced Alterations in Bone Marrow and Spleen of Rats

Sawsan Ahmed Abd Elhalim, Hayat Mohamed Sharada, Ibrahim Abulyazid, Wael Mahmoud Aboulthana, Sohaila Talaat Abd Elhalim.


Many anticancer drugs including cyclophosphamide (CYP) exhibit potentially life-threatening effects on the immune and hematopoietic systems. The spleen and lymphatic tissues are the most sensitive components of immune system. In the present study, it was verified that CYP caused significant (P

Key words: Cyclophosphamide, Bone marrow, Spleen, Ceratonia siliqua, Electrophoresis, Isoenzymes.

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