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Effects of Toxocara canis Infection and Albendazole Treatment on Oxidative/Nitrosative Stress and Trace Element Status in Dogs

Priyanka Mahadappa, Sahadeb Dey.

The present study was conducted with the objectives of studying the oxidative/nitrosative and trace element alterations in naturally Toxocara canis infected dogs before and after treatment with albendazole and to explore the effect of albendazole treatment on oxidative/nitrosative status in healthy dogs. Six naturally infected dogs with T.canis were selected for the present study. These cases were treated with albendazole @ 25 mg/kg orally for 3 consecutive days and monitored weekly up to 28 days of post treatment. Six apparently healthy dogs acted as healthy control and were also treated with albendazole @ 25 mg/kg orally. A highly significant increase in NO (p< 0.01) and LPO (p

Key words: Albendazole, Dog, Oxidative/Nitrosative Stress, Toxocara canis, Trace Elements

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Journal of Interdisciplinary Histopathology


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