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Research Article

Open Vet J. 2025; 15(12): 6401-6407


Effect of ashwagandha (Withania somnifera) on endocrine and reproductive traits in Awassi sheep

Ashraf Kamil Azeez, Afraah Mustafa Mohammad, Nawar Bahaa Abdul-jabbar, Ghadir Kamil Ghadir, Zaid Khalid Alani.



Abstract
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Background:
Although ashwagandha, or Withania somnifera, is used as a broad-spectrum treatment to treat a wide range of illnesses, including reproductive issues, and to improve fertility, it is also considered a potent adaptogen and anti-stressor that may assist improve physical performance.

Aim:
The aim of the study was to evaluate the effect of two doses of ashwagandha on physiological parameters and reproductive parameters in Awassi sheep in Iraq.

Methods:
Thirty Awassi ewes were randomly assigned to three groups (10 each): a control (placebo), 300 mg/day ashwagandha, and 600 mg/day ashwagandha, for 60 days. Physiological (hepcidin, growth hormone, insulin, TSH, T3, T4) and reproductive (estrogen, progesterone, FSH, LH) parameters were measured on days 0, 30, and 60, while body weights were recorded weekly.

Results:
The experimental data demonstrated that both experimental groups showed increased growth hormone levels along with decreased hepcidin and Insulin levels, thyroid hormone levels (T3 and T4) increased significantly (P

Key words: Ashwagandha; Awassi sheep; Physiological traits; Reproductive capabilities.







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