BACKGROUND AND OBJECTIVES: Levobupivacaine and Ropivacaine are the two recently introduced local anaesthetics alternatives to Bupivacaine in clinical practice. The present study has been conducted to compare the efficacy of intrathecal isobaric levobupivacaine 0.5% and isobaric ropivacaine 0.5% in terms of sensory and motor blockade characteristics, intraoperative haemodynamics stability and side effects if any..
METHODOLOGY : A prospective randomized double blind study was conducted in 60 ASA grade I-II patients in age groups of 18-60 years undergoing lower limb surgeries. Patients were divided in 2 groups of 30 patients each. Group L received 3ml isobaric levobupivacaine 0.5% whereas Group R received 3 ml isobaric ropivacaine intrathecally.Patients were assessed for onset and duration of sensory & motor blockade ,intraoperative haemodynamic parameters and side effects .
RESULTS:- There was no difference in demographic data, onset and peak effect of sensory &motor block in both groups (P>0.05). Duration of sensory & motor block and time to two segment regression were significantly longer in Group L than Group R (p
Isobaric, Levobupivacaine, Ropivacaine
Procedures to Evaluate the Role of Heparan Sulfate on the Reactivity of Resistance and Conductance Arteries Ex Vivo.
Cho JM, Ly K, Ly S, Park SK, Babu PVA, Balagurunathan K, Symons JD
Methods in molecular biology (Clifton, N.J.). 2022; 2303(): 495-511
Mass Spectrometry-Based Quantitative Cysteine Redox Proteome Profiling of Isolated Mitochondria Using Differential iodoTMT Labeling.
Giese J, Eirich J, Post F, SchwarzlÃ¤nder M, Finkemeier I
Methods in molecular biology (Clifton, N.J.). 2022; 2363(): 215-234
A Compendium of Murine (Phospho)Peptides Encompassing Different Isobaric Labeling and Data Acquisition Strategies.
Popow O, Liu X, Haigis KM, Gygi SP, Paulo JA
Journal of proteome research. 2021; ():
Resolving Severe Elemental Isobaric Interferences with a Combined Atomic and Molecular Ionization Source-Orbitrap Mass Spectrometry Approach: The Sr and Rb Geochronology Pair.
Hoegg ED, Godin S, Szpunar J, Lobinski R, Koppenaal DW, Marcus RK
Analytical chemistry. 2021; ():
Comparison of intravenous regional anaesthesia with lidocaine and ropivacaine in dogs.
Imani Rastabi H, Mirzajani R, Givi ME, Mohammadpoor M
Veterinary medicine and science. 2021; ():