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Original Article



Factors Influencing Clinical Manifestations as Predictors of Dengue Severity: A Patient-Based Study

Sumaya1, †, Papri Biswas1, †, Banya Plaboni1, Md. Rahian Hossain1, Umme Salma1, Tanvir Ahmmed2, Md. Fakhrul Islam Maruf3, Nishat Tamanna Omi3, Erjan Aziz Khan1, 4, Shifat Jahan Shipu5, Jaber Ahmed Hridoy5, Md. Rofiqul Islam6, Md. Akibul Hasan1*.



Abstract
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Dengue fever presents with a broad spectrum of symptoms, ranging from mild to life-threatening complications. Understanding the clinical symptoms based on demographic and biochemical predictors of severity is vital for early intervention. A cross-sectional study was conducted among 375 dengue patients. Clinical symptoms, demographic profiles, platelet counts, and infection history were analyzed. Then the level of severity has been categorized as Dengue Fever (DF), Dengue Fever with Warning Signs (DFWS), and Severe Dengue (SD), emphasizing warning signs like abdominal pain, nausea/vomiting, and hemorrhage as indicators of severity. Results show males were more affected, while females exhibited more severe symptoms, including hypotension, and hemorrhage. Pediatric patients showed higher prevalence of warning signs, such as abdominal pain and poor appetite, suggesting increased severity risk. Among occupations, homemakers had the highest incidence of warning signs, potentially due to delayed healthcare access and domestic mosquito exposure. Severe thrombocytopenia (

Key words: Dengue fever, Clinical symptoms, Dengue severity, Platelet count, Secondary infection, Mortality rate







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