Abstract

Aim: To evaluate the clinical signs and biochemical parameters associated with fibrous osteodystrophy in goats and to assess the distribution of the disease based on breed, sex, and season in a hospital-based setting.
Method: This case series was conducted at Chattogram Veterinary and Animal Sciences University (CVASU) in Chattogram, Bangladesh, with data collected from March to August 2017 and analyzed later that year, to document clinical manifestations and alterations in biochemical parameters—namely calcium, phosphorus, and alkaline phosphatase levels—in goats diagnosed with the disease. The study also examined disease distribution based on breed, sex, and season. Diagnosis was established through clinical history, physical examination, and laboratory evaluation. Biochemical analysis was performed using Randox clinical chemistry assay kits.
Results: Out of ten diagnosed cases, the highest incidence (50%) was recorded during the rainy season (August). Jamunapari and crossbred goats were more frequently affected (33%) than Black Bengal goats (11%). Males represented 66% of the cases. Clinical manifestations included mandibular swelling (50%), joint swelling (20%), leg deformities (40%), tongue protrusion (20%), and open mouth (10%). Biochemical findings revealed variable serum calcium and phosphorus levels, with elevated ALP values indicating increased bone turnover.
Conclusions: Fibrous osteodystrophy in goats was predominantly observed in intensively reared male goats during the rainy season. The clinical and biochemical findings are consistent with nutritional secondary hyperparathyroidism. Proper dietary management, especially maintaining a calcium-to-phosphorus ratio of 2:1, is crucial for prevention and control.

Key words: Biochemical parameters, clinical findings, fibrous osteodystrophy, goats, metabolic bone disease