Abstract

This study aimed to demonstrate the effect of honey on the oxidative stress in the brain of sleep-deprived rats. Twenty–five (25) 6-week-old male Wistar rats were randomly divided into five groups to be subjected to sleep deprivation and recovery for 5 days each. Group I (Normal control); Group II: sleep deprivation (SD); Group III: sleep deprivation and recovery (SD+SR); the 3 groups received 10ml/kg distill water orally each; Group IV: sleep deprivation and honey (SD+Honey), Group V: sleep deprivation, recovery with honey (SD+SR+Honey) both groups received honey (1g/kg body weight) orally once daily. There was a significant decrease (P

Key words: Keywords: Sleep; Sleep deprivation; Honey; Oxidative stress