Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles

Open Access

Original Research

Patho-Morphological Changes in Liver, Kidney and Brain of Broiler Birds Due to Chlorpyrifos Intoxication

Henna Wani, Shafiqur Rehman, Shabu Shoukat, Navdeep Kour, Bisma Ayoub.

The present study was conducted to investigate pathomorphological changes in chlorpyrifos toxicity in broilers. Group I served as control while group II, III and IV birds were given Chlorpyrifos @3.2,1.6 and 0.64 mg/kg, respectively, orally in corn oil for a period of 6 weeks. The birds were sacrificed by humane method. Representative tissues from the affected regions of various organs were collected in 10% buffered formalin. Tissue samples were processed for routine paraffin embedding technique and 5 micron thin section were stained with Haris’ Haematoxylin and Eosin stain. Histopathologically, liver of all the treatment group birds showed hepatocytic degeneration and necrosis, Mononuclear cell infiltration (MNC) and fibrosis in portal area, degeneration and swelling of epithelial cells of Proximal Convoluted Tubule’s obliterating lumen and presence of MNC in kidneys, engorgement of cerebral blood vessel with increased perivascular space,shrunken deeply eosinophilic neurons, MNC leading to leptomeningitis in brain.

Key words: Broiler Birds, Chlorpyrifos, Histopathology, Mononuclear Cells

Share this Article

Applied Medical Research


BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright © ScopeMed® Information Services.