Home|Journals|Articles by Year|Audio Abstracts
 

Original Research



Considerations on pathophysiology of primary dysmenorrhea under the light of alterations in complete blood count parameters

Serkan Bodur, Mine Kanat Pektas, Vuslat Lale Bakir, Mehmet Ferdi Kinci, Ibrahim Alanbay, Ozgur Dundar.




Abstract

The present study strives to evaluate how the components of complete blood count are altered in women with primary dysmenorrhea. This is a cross-sectional analysis of 155 women with primary dysmenorrhea and 155 women without dysmenorrhea. The primary dysmenorrhea and control groups were matched with respect to age and body mass index. When compared with the controls, the women with primary dysmenorrhea had a significantly younger menarche age, longer menstrual duration, higher leukocyte counts, higher neutrophil counts, and elevated MPV values (p=0.010, p=0.022, p=0.014, p=0.011 and p=0.04 respectively). The logistic regression analysis demonstrated that women with primary dysmenorrhea were more likely to have a younger menarche age (OR=2.14, 95% CI=0.971-3.346, p=0.018), longer menstrual duration (OR=1.91, 95% CI=0.988-2.308, p=0.044), higher leukocyte counts (OR= 2.90, 95% CI=1.040-3.788, p=0.007), and elevated MPV values (OR=3.17, 95% CI=2.056-9.128, p=0.001). The sensitivity and specificity of this model were 84.6% and 77.3%, respectively. Leukocytosis and increased MPV are might be associated with the inflammatory and vasoconstrictory pathogenesis of primary dysmenorrhea, but this result should be confirmed in the future researches.

Key words: Dysmenorrhea, mean platelet volume, platelet distribution width






Full-text options


Share this Article


Online Article Submission
• ejmanager.com




ejPort - eJManager.com
Refer & Earn
JournalList
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.