Abstract

Background: We recently suggested TaibUVID nutritional supplements (containing natural honey, Nigella sativa, chamomile, costus, fennel, and/or senna) of prophetic medicine as adjuvants to pharmacological treatments to potentiate immunity and combat the SARS-COV-2 virus and COVID-19 pandemic. The present study aims at assessing the safety and effectiveness of taking adjuvant TaibUVID nutritional supplements.
Methodology: A prospective controlled trial was not applicable. However, a retrospective data analysis of ten confirmed COVID-19 patients (many of them have radiological findings) in Egypt was carried out. Patients knew about the TaibUVID nutritional supplements via social media. An online questionnaire was also distributed via social media to investigate patients’ opinions regarding the safety and effectiveness of taking adjuvant TaibUVID nutritional supplements. Paired sample t-test and Statistical Package for the Social Sciences version 16 were used for data analysis.
Results: TaibUVID induced lymphocytosis and increased the percentage of lymphocytes from 21% to 53.4% within few days, i.e., may increase B lymphocytes (humoral immunity) and T lymphocytes (cell-mediated immunity). COVID-19 patients (n = 3) taking pharmacological treatments only needed a significantly longer duration (p < 0.05) till the beginning of improvement or death (9.66 ± 1.33 days) versus 3.5± 0.22 days for COVID-19 patients who received pharmacological treatments with TaibUVID nutritional supplements (n = 10, majority were physicians). COVID-19 patients (n = 3, all were physicians) taking pharmacological treatments only needed a significantly longer duration (p < 0.05) till complete recovery or death (12.33 ± 2.73 days) versus 7.3 ± 1.01 days for those receiving pharmacological treatments with TaibUVID nutritional supplements (n = 10, majority were physicians). In the questionnaire, 33 out of 40 patients (82.5%) reported no side effects after TaibUVID administration. 7 patients (17.5%) reported few side effects (hyperglycemia and diarrhea) after TaibUVID intake. Diarrhea may be due to senna (recommended but optional). Hyperglycemia may occur with non-natural honey. 38 patients (90%) reported improvement by 25%-100% after intake of TaibUVID nutritional supplements. 20 patients (50%) confirmed getting health benefits after TaibUVID inhalation therapy. 22 patients (55%) reported they know other COVID-19 patients not taking TaibUVID supplements and had delayed improvements.
Conclusion: TaibUVID enhanced immunity and potentiated a safe rapid recovery of COVID-19 infection. It is strongly advisable to add TaibUVID nutritional supplements to pharmacological protocols to fasten patients' recovery. TaibUVID supplements are advisable for public and contacts prophylaxis. "TaibUVID for all" health campaigns are recommended. More clinical research studies are recommended. Limitation: This study is limited by the few number of patients and lack of detailed investigations.

Key words: COVID-19, TaibUVID, TaibUVID Forte, TaibUVID inhalation therapy, Nigella sativa, natural honey, chamomile, senna, fennel, costus