Drug-induced urinary incontinence is involuntary leakage of urine, not life-threatening but adversely affecting the quality of life. Despite urinary incontinence is reported as one of the side effects of selective serotonin reuptake inhibitors (SSRIs), there have only been few cases of urinary incontinence associated with SSRIs reported in literature. We present a case report of urinary incontinence associated with sertraline with possible underlying mechanisms which resolved with sertraline discontinuation and switch to fluoxetine. Therefore, clinicians should be awake and question side effects of urinary incontinence that occurs rarely but adversely affect the quality of life.
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