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Review Article

J Med Allied Sci. 2017; 7(2): 76-81


Review on diagnosis of acute pancreatitis

Ikenna Kingsley Uchendu, Chidozie Elochukwu Agu, Oliver Chukwuma Orji, Mercillina Chioma Offor, Tochi Faith Nwosu.




Abstract

Acute pancreatitis is an acute inflammation of the pancreas with varia-ble involvement of surrounding tissues and/or distant organs. Acute pancreatitis is mild and resolves itself without serious complications in 80% of patients; however it has complications and mortality in about 20% of patients despite the aggressive intervention. This paper covers the various etiologies attributing to acute pancreatitis, pathophysiology of acute pancreatitis and the diagnostic markers used for acute pan-creatitis. The diagnostic markers include: Amylase, Lipase, Trypsinogen, Interleukin-6, C reactive protein, Procalcitonin, Polymorphonuclear Elastase (PMN Elastase), Trypsin Activation Pep-tide (TAP), Trysinogen-2, Hepcidin, Copeptin, Soluble E-Selectin (sES) and Soluble Thrombomodulin (sTM), and Serum Intercellular Adhesion Molecule-1 (ICAM-1).

Key words: Acute pancreatitis, Amylase, C-reactive protein, Diagnostic markers, Interleukin-6, Lipase, Trypsinogen






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