Influence of Systemic Ampicillin or Pen-Strep and Intrauterine Oxytetracycline Combined with Systemic PGF2α or Estradiol on the Clinical Recovery and Fertility of Crossbred Kenana Affected by Clinical Metritis

AJVS. 2025; 86(0): 102-110

Ibrahim M.I. Mohammedain, Reham Waheeb, Wael M. Noseir, Sayed A. Hattab.

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The study aimed to evaluate the effects of four therapies for clinical metritis (CM) treatment on recovery and reproductive performance in crossbred Kenana × Holstein dairy cows in Khartoum, Sudan. A total of 87 cows with CM were divided into six groups: G1 (control negative - CN) (n = 10) with healthy cows; G2 (control positive - CP) (n = 10) with untreated CM cows; G3 (Ampicillin treated) (n = 14); G4 (Penicillin and streptomycin treated) (n=17); G5 (Oxytetracycline and PGF2α treated (OTC+ PGF2α)) (n=18); and G6 (Oxytetracycline and estradiol benzoate treated OTC+EB) (n=18). The results indicated that the OTC + EB and Penicillin + streptomycin groups had significantly shorter intervals from treatment to service (P Key words: Antibiotics, hormones, clinical metritis, reproductive performance, cross, kenana