Nowadays, one of the main areas in internal disease treatment is preventive medicine, which includes the risk measurement method. This method is often used in cardiology to assess both the possibilities of disease emergence and its progression or complicated course. The purpose of this study was to investigate the possibilities of identifying factors of cardiovascular risks in people with GERD and obesity. Eighty patients, whose average age was 47.1±5.5, were examined. The results of the study allowed distinguishing prognostic factors of cardiovascular risks for persons with isolated forms of GERD and obesity, as well as their comorbidity. The developed formulas and models allow assessing the risk of cardiovascular diseases individually for obesity, gastroesophageal reflux disease, and the combination thereof. We determined the risk of cardiovascular diseases in cases of obesity and in GERD patients, which is a result of the features of chronobiologic indicators of the organism, the metabolic profile, and the degree of deleterious lesions of the esophageal mucosa in patients. The presented model characterizes the probability of emergence of cardiovascular diseases in patients with non-cardiac pathologies. This study can be used to design new methods of prevention of cardiovascular events.
Key words: cardiovascular disease model, chronobiologic indicators, discriminant analysis method, gastroesophageal reflux disease, obesity
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