Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles

Open Access

Original Research

Med Arch. 2010; 64(5): 269-273

The Role of Exercise Test in Stratifying the Risk of Asymptomatic Patients with Moderate/Severe Aortic Stenosis

Zumreta,Kusljugic,,Fahir,Barakovic,,Mirza,Dilic,,Larisa,Dizdarevic-Hudic,,Elnur,Smajic,,Jasmin,Caluk,,Sevleta,Avdic,,Suada,Mulic,,Maida Isabegovic,,Melika,Avdagic,,Katarina,Kovacevic-Divkovic,,Amira,Bijedic.

Objectives: The role of exercise test in risk stratifying of asymptomaticpatients with moderate and severe aortic stenosis (AS) in recentliterature is still controversial. The aim of this study was to evaluatethe role of exercise test in stratifying the risk of patients with moderate tosevere aortic stenosis. Methods: At the Internal Medicine Clinic, Departmentof Cardiology in Tuzla, in the period from January 2008 until January 2010was followed 33 patients with clinical and echocardiographic parametersof moderate to severe asymptomatic aortic stenosis (mean effective orificearea EOA 0,90,34 cm2). In statistical analysis we used descriptive statistics,t-test, chi-square test and Kaplan-Meier life table for predictive values, sensitivityand specificity. A significance level of 0.05 was used. Results: Twopatients were excluded due to exclusion criteria, so 31 patient was followedup during 12 months period. Eighteen patients (58%) with EOA Ł 0,8cm2had limiting symptoms during the test. During follow-up period, 11 patientsdeveloped serious spontaneous symptoms, and out of them 8 patients underwentsurgical valve replacement, one patient died (sudden cardiac death),and 2 patients had serious complications (ischemic cerebral stroke). Twentypatients remained asymptomatic. The highest positive predictive accuracyhad EOAŁ 0,8cm2 with limiting symptoms and it was 85%. The highestnegative predictive accuracy had ST depression. Conclusion: only limitingsymptoms along with EOAŁ 0,8cm2 had positive predictive accuracy.

Key words: asymptomatic aortic stenosis, exercise test, prognosis

Share this Article

Applied Medical Research


BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.