Prevalence and Serological Predictors of Liver Fibrosis in Vietnamese Chronic Hepatitis B Patients with Persistently Normal or Mildly Elevated Aminotransferase Level

Med Arch. 2025; 79(2): 147-154

doi: 10.5455/medarh.2025.79.147-154

Tien Duc Dao, Hieu Van Tran, Khai Hoang Nguyen, Khien Van Vu.

Abstract	Download PDF		Post
Background: Chronic hepatitis B (CHB) remains a significant health concern, especially in low- and middle-income countries. Some CHB patients with normal or mildly elevated ALT may have advanced liver fibrosis, which often goes undetected. Objective: The aim of this study was to assess the prevalence of significant fibrosis and the diagnostic accuracy of serum markers in CHB patients with ALT Key words: Chronic hepatitis B, liver fibrosis, APRI, platelet count, non-invasive biomarkers, Vietnam.