Home|Journals|Articles by Year Follow on Twitter

Directory for Medical Articles

Open Access

Original Article

Synthesis and evaluation of silver nanoparticles using Cymodocea rotundata against clinical pathogens and human osteosarcoma cell line

Jayanthi Abraham, Shantanu Saraf, Vakas Mustafa, Yugal Chaudhary, Silambarasan Sivanangam.

Objective: To evaluate the silver nanoparticles (AgNPs) synthesis by aqueous extract of Cymodocea rotundata against clinical pathogens and human osteosarcoma cell line. Methods: In the present study, AgNPs were synthesized by Cymodocea rotundata by reducing 1 mM silver nitrate (AgNO3) solution. The green synthesized AgNPs were characterized by UV-vis spectroscopy, Atomic force microscopy (AFM), scanning electron microscopy (SEM), Fourier infrared spectroscopy (FTIR) and X-ray diffraction (XRD). Results: FTIR spectroscopy confirmed the presence of protein as the stabilizing agent surrounding the AgNPs. Morphologically, the nanoparticles were found to be spherical with an average particle size distribution of 24.2 nm. The green synthesized AgNPs showed powerful antioxidant properties in in-vitro antioxidant assays and effective in inhibiting human pathogens. The AgNPs also showed potent cytotoxic effect against MG63 cell lines with an IC50 value of 25.31 μg ml-1 which was confirmed by MTT assay. Conclusions: The results support the advantages of using bio-green method for synthesizing AgNPs with antioxidant, antimicrobial and cytotoxic activities are simple and cost effective.

Key words: Silver nanoparticles, Cymodocea rotundata, FTIR, SEM, MG63 cell line

Similar Articles

Improving cell transplantation by understanding and manipulating the phagocytic activity of peripheral glia.
Nazareth L, St John J, Ekberg J
Neural regeneration research. 2022; 17(2): 313-314

Effects of selenium-containing compounds on Cu/Zn-induced neuronal cell death and potential application as therapeutic agents for neurological diseases.
Tanaka KI, Shimoda M, Kawahara M
Neural regeneration research. 2022; 17(2): 311-312

Ca2+-dependent protein acyltransferase DHHC21 controls activation of CD4+ T cells.
Bieerkehazhi S, Fan Y, West SJ, Tewari R, Ko J, Mills T, Boehning D, Akimzhanov AM
Journal of cell science. 2022; 135(5):

Cell cycle exit and neuronal differentiation 1-engineered embryonic neural stem cells enhance neuronal differentiation and neurobehavioral recovery after experimental traumatic brain injury.
Wang R, Yang DX, Liu YL, Ding J, Guo Y, Ding WH, Tian HL, Yuan F
Neural regeneration research. 2022; 17(1): 130-136

Functionality of a bicistronic construction containing and genes encoding β-hexosaminidase A for cell-mediated therapy of GM2 gangliosidoses.
Shaimardanova AA, Chulpanova DS, Solovyeva VV, Aimaletdinov AM, Rizvanov AA
Neural regeneration research. 2022; 17(1): 122-129

Full-text options

Add your Article(s) to Indexes
• citeindex.org

Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.