Abstract

In this study, we investigated the relationship between nasal polyps (NP) and NP density using the systemic inflammatory index (SII), systemic inflammatory response index (SIRI), eosinophil-lymphocyte ratio (ELR), neutrophil-lymphocyte ratio (NLR), and platelet-lymphocyte ratio (PLR). Of the 132 patients included in this study, 67 had NP, and 65 were included in the control group. The mean age of the study group was 44.58 ± 14.15 years, and that of the control group was 42.46 ± 13.59 years. An endoscopic staging method was used to determine NP density. The SII, SIRI, ELR, NLR, and PLR values in the NP and control groups were calculated and statistically compared. The study group was stratified according to endoscopic NP density. The mean NLR and ELR values were significantly higher in the study group. The mean NLR and ELR values in the study group were 1.72 ± 0.66 and 1.46 ± 0.50, respectively, and in the control group, they were 1.46 ± 0.50 and 0.13 ± 0.06 (p=0.007, p=0.0001). The higher mean PLR, SII, and SIRI values in the study group were not statistically significant (p>0.05). The leukocyte count was significantly higher in the stage 3 patient group. No statistically significant relationship was found between staging and mean NLR, ELR, PLR, SII, and SIRI values (p>0.05). NLR and ELR values derived from hemogram data can serve as markers of nasal polyps.

Key words: Blood cell count, inflammation, nasal polyps