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Correlation Between Clot Load Burden with Neutrophil-Lymphocyte and Platelet-Lymphocyte Ratios in Patients with Acute Pulmonary Embolism

Mehmet Burak Cildag, Songul Cildag.




Abstract
Cited by 2 Articles

Background: The correlation between neutrophil-lymphocyte ratio (NLR) and acute pulmonary embolism (APE) related mortality, platelet-lymphocyte ratio (PLR) and clinical severity classification of APE were demostrated. Clot load also burden one of the prognostic criteria of pulmonary embolism.
Method: The pulmonary arterial computed tomographic obstruction index ratio (PACTOIR) was calculated in 62 patients diagnosed with APE, retrospectively. Patients were divided into two groups according to their PACTOIR values. NLR and PLR were calculated from the blood samples collected on the day of diagnosis.
Results: Mean PACTOIR, mean NLR and mean PLR of all patients with APE were calculated as 23.58%, 4.4 and 186.5, respectively. A positive correlation was observed between PACTOIR and NLR and PLR. A statistically significant difference was found between the NLR and PLR levels of low and high PACTOIR groups.
Conclusion: A statistically significant correlation was found between PACTOIR and NLR and PLR in patients with APE. According to the findings of our study, NLR and PLR ratios may give an idea about the thrombus load in patients with clinically suspected APE.

Key words: Acute Pulmonary Embolism, Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio.






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