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Original Article

J App Pharm Sci. 2017; 7(7): 158-167


Synthesis, Characterization and Anticonvulsant Activity of Some Novel 4, 5-Disubstituted 1,2,4-Triazole Derivatives

Yasmin Khatoon, Mohammad Shaquiquzzaman, Vijender Singh, Mohammad Sarafroz.




Abstract

Synthesis of some newer chemical entities and evaluation for their anticonvulsant activity by the subcutaneous pentylenetetrazole and the maximal electroshock seizure screen methods.

Key words: 1, 2, 4-Triazoles, Anticonvulsants, Neurotoxicity, Lipophilicity






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