Abstract

A Fitness Fatness Index (FFI) was recently (2016) developed, with FFI calculated as cardiorespiratory fitness (CRF) divided by waist-to-height ratio (WHR). No study has evaluated the effects of FFI on cancer-specific mortality risk, which was this study’s purpose. Data from the 1999-2006 National Health and Nutrition Examination Survey were employed, with follow-up through 2011. Among the 9,974 participants, 138 died of cancer over the follow-up period; median follow-up period was 105 months (IQR: 81-129). In a Cox proportional hazard model, for every 1 FFI increase, participants had an 8% reduced hazard of cancer-specific death (HR=0.92; 95% CI: 0.88-0.96; P

Key words: Epidemiology; survival; exercise; central obesity