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Original Article

J App Pharm Sci. 2017; 7(8): 175-182


Pharmacological Assessment, Green synthesis and Characterization of Silver Nanoparticles of Sonneratia apetala Buch.-Ham. Leaves

Peddinti Nagababu, Vanga Umamaheswara Rao.

Abstract
The present investigation involved the screening and evaluation of S. apetala leaf crude extracts for the phytochemicals, antibacterial activity and antioxidant activity. Green synthesis of AgNPs using aqueous leaf extract, Characterization and antibacterial activity of synthesized nanoparticles were also carried out in the study. Outcome of all the experiments carried out suggests the existence of most of the phytochemicals in the leaves and are having some important biological activities. Further work is needed to isolate, purify and identify the exact active principle which is the cause for the biological activities. The Green synthesis is a simple, low cost and ecofriendly approach without any huge inputs in terms of energy. This is the first report of Green synthesis of silver nanoparticles for this plant. Being exhibiting greater antibacterial activity, phytochemical based nanoparticles may stand as a potential remedy in developing drugs against antibiotic resistant bacteria.

Key words: Sonneratia apetala; Phytochemical screening; Antioxidant activity; Silver nanoparticles; FTIR spectroscopy; Antibacterial activity.



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