The quality-switched 1064-nm neodymium-doped yttrium aluminum garnet (QS 1064-nm Nd:YAG) laser is widely used to treat many skin conditions. Originally, it was used for the treatment of pigmented lesions such as nevus of Ota and tattoo removal. Furthermore, it is widely used in skin rejuvenation and melasma treatment. In daily practice in Saudi Arabia and the Middle East, it is commonly used for hair removal because of its good efficacy and safety profile. According to the advances in the use of QS 1064-nm Nd:YAG, more complications are seen. Hypopigmentation has been reported in multiple case reports as one of the complications after tattoo removal, melasma treatment, and skin rejuvenation. In this case series, we are presenting four cases of hypopigmentation secondary to hair removal by QS 1064-nm Nd:YAG. Three cases were facial hypopigmentation, and one was in the arms. In conclusion, there are no identified risk factors and no standardized measures to avoid this undesired complication.
Key words: Laser; Hair Removal; Hypopigmentation