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Original Research

RMJ. 2018; 43(2): 213-216

Liver dysfunction and its effect on renal function: A hospital based study from Khyber Pakhtunkhaw, Pakistan

Mohammad Yousaf.

Objective: To study the effect of extent of liver dysfunctions on the renal function in non-pregnant women of Khyber Pakhtun Khwa, Pakistan.
Methodology: The study population comprised of 240 non pregnant women in the age group of 18-60 years. Control Group (CG) consisted of 126 individuals, while 114 were taken as Study Group (SG). The data regarding age, BMI and medical history was collected from the patients through a well-designed data entry form using purposive sampling method. 5 ml of fasting venous blood sample was collected from each patient and was analyzed for ALT, AST, urea and creatinine, using Standard protocols. The data were statistically analyzed on SPSS version 21.0.
Results: Significant differences were found in the serum urea and creatinine of CG & SG. The mean serum urea & creatinine of SG (serum urea: 33.30 mg/dl, CRT: 1.34 mg/dl) was found higher than the CG (serum urea: 28.41 mg/dl, CRT: 1.19 mg/dl).
Conclusions: Renal markers were found higher in Study Group (SG) population than in Control Group (CG).

Key words: Creatinine, urea, aspartate transaminase, alkaline phosphatase

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