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In vivo anti-inflammatory activity of the hydro-ethanolic extract of Adansonia digitata leavesMbaye Sene, Ibrahima Diouf, Mamadou Ndiaye, Awa Ba, Fatoumata Ba, Habibou Sow, Ndeye Absatou Diaw, Awa Ndiaye, Modou Oumy Kane, Mamadou Sarr, Madieye Sene. Abstract |  Download PDF | Cited by 0 Articles |  Post | Background:
Adansonia digitata, a plant of the Bombacaceae family is frequently used in traditional African medicineto treat various inflammatory conditions.
Aim:
This study aimed to evaluate the anti-inflammatory activity of a dry hydro-ethanolic extract of leaf powder(ADF), reconstituted with physiological water.
Methods:
The in vivo model of carrageenan-induced rat paw edema method is used. The rats received the extract at a dose of 10 mg/kg, while acetylsalicylic acid (10 mg/kg) was used as a reference, and the physiological water (1 ml/100g) was used as a control.
Results:
After oral administration, the extract significantly prevented edema of the rat paw at the 3rd and 5th hour (p
Key words: Inflammation, Adansonia digitata, In vivo, Edema, Carrageenan
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