Home|Journals|Articles by Year Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

Original Article

J Liaquat Uni Med Health Sci. 2006; 5(1): 18-23


UNILATERAL NASAL OBSTRUCTION CAUSED BY SINO-NASAL NEOPLASTIC LESIONS

Syed Mosaddaque Iqbal and Syed Iqbal Hussain.

Abstract
OBJECTIVE: To report pattern of unilateral nasal obstruction caused by sino-nasal neoplasms
seen in two teaching hospitals in Sindh, Pakistan.
DESIGN: A case series.
SETTING: Ear, Nose and Throat (ENT) departments of Jinnah Postgraduate Medical Centre, Karachi
and People’s Medical College, Nawabshah between June 1995 to June 1998.
METHODS: This study included 51 patients who presented with unilateral nasal obstruction persistantly
for more than eight weeks. A proforma was designed to note the complaints, pinpoint
the cause and look at the outcome of the treatment and prognosis. Thus, a detailed history of
patients was undertaken through clinical examination, laboratory investigations e.g. blood profile,
urine analysis, radiological (common and special) imaging, biopsy and histopathology.
RESULTS: Neoplastic lesions of the nose and paranasal sinuses were found in 51 patients. This
included 16 (31.37%) females and 35 (68.62%) males with an average age of 37 years. Benign
lesions were 19 (37.25%) and 32 (62.75%) were malignant including single case of schwanoma,
two cases of squamous papilloma and three patients with fibrous dysplasia while inverted
papilloma was seen in six and nasopharyngeal angiofibroma in seven patients. Commonest malignant
lesion was squamous cell carcinoma seen in 30 (58.82%) patients. Maxillary sinus was
involved in 30 cases and 2 of them were arising from the ethmoid sinus and nasal cavity, and
were found to be adenocarcinoma. For benign lesions, wide surgical approach was adopted and
except one case of inverted papilloma which reccurred, rest were cured completely. Radical and
oncologically sound surgical resection combined with radiation therapy remained the treatment
of choice for all the malignant lesions. Local recurrence was seen in two cases. Only one patient
died after 8 months due to distant metastasis. Two patients were lost to follow up after 25
months.
CONCLUSION: Neoplastic lesions especially the benign tumors, promptly treated via wide surgical
approach, mostly cure the lesion with negligible complication or no recurrence. Malignant
lesions of the nose and sinuses are very often diagnosed in advanced T-stages (intracranial or
intraorbital extentions) due to non-specific symptoms and have a poor overall prognosis even
in the advances in surgical techniques, radiation therapy and new chemotherapeutic agents.

Key words: Neoplasm. Nose. Sinus. Malignancy.


Full-text options

Full-text Article


Share this Article


Readers of this article also read the following articles
»Risk Factors and Socio-Demographic Profile in Patients with Attempted Suicide in a Tertiary Care Centre, Bengaluru: A Cross-Sectional Study
»Influence of age and body mass index on nerve conduction velocity in median nerve and relation among them in the healthy population of Indore region
»Using Double Dose of GnRH for Reducing Incidence of Cystic Ovaries in Cows
»Iron Deficiency Anaemia and Its Predisposing Causes among Women Undergoing Antenatal Checkup at a Tertiary Care Hospital in Allahabad
»THE SCOPE OF RESEARCH IN AYURVEDA
»Vermicompost management: An alternative to meet the water and nutritive demands of tomato under greenhouse conditions
»Bacterial Flora of Skin Affections Cases of Freshwater Fish
»A Study on Clinical Profile, risk factors and Mortality in Hypertensive Intracerebral Hemorrhage in a tertiary care hospital in Surat city
»VACCINATION STRATEGIES IN PATIENTS WITH BONE MARROW TRANSPLANTATION
»Application of colour parameters for assessing the quality of Arabica and
Robusta green coffee
»Antibacterial activity of organic extracts from Zinnia peruviana (L.) against
gram-positive and gram-negative bacteria



Advertisement
American Journal of Diagnostic Imaging

SUBMIT YOUR ARTICLE NOW




ScopeMed.com
BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright © ScopeMed® Information Services.