Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles

Open Access

Original Article

J Liaquat Uni Med Health Sci. 2007; 6(3): 103-108


K. Altaf Hussain Talpur, Abdul Aziz Laghari, Arshad Mahmood Malik and Sangrasi Ahmed Khan.

OBJECTIVE: To determine the diagnostic accuracy of FNAC versus histopathology in various
body lumps.
DESIGN: Quasi-experimental study.
SETTING: Surgical department of Liaquat University Hospital Jamshoro/ Hyderabad, Sindh-
Pakistan, from January 2003 to December 2005.
PATIENTS AND METHODS: One hundred and sixty five patients with lumps at various body
sites were studied. Patients were evaluated by history, examination and investigations. Then
they underwent for FNAC followed by open biopsy. Reports of FNAC and histopathology were
compared and accuracy of FNAC assessed.
RESULTS: Out of 165 cases, 92 (55.76%) had neck lumps (with thyroid and extra-thyroid swellings,
46-cases each), 35 (21.21%) breast lumps, 10 (6.06%) parotid swellings and 11 (6.66%)
cases had axillary lump as main sites for FNAC, along with various other parts of body. FNAC
revealed benign neoplastic conditions in 13.94% of cases, malignancy in 18.18%, tuberculous
lymphadenopathy in 14.54%, goitre in 18.79%, and inflammatory lesions in 11.52% of cases as
main lesions with false negative results of 18.78% and false positive result of 0.60%, whereas
histopathology revealed malignancy in 24.85%, benign neoplastic lesions in 20.0%, goitres in
19.39%, tuberculous lymphadenopathy in 23.03% as main disease problems.
CONCLUSION: FNAC has high sensitivity and specificity in diagnosis of various body lumps.
Findings of this study are almost comparable to histopathology however, FNAC shows high
false negative results which may be due faulty sampling technique or lack of expertise.

Key words: Lumps, FNAC, Biopsy, Histopathology, Sensitivity, Specificity.

Share this Article

Oxidants and Antioxidants in Medical Science


BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.