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Original Article

J Liaquat Uni Med Health Sci. 2008; 7(2): 124-128


Spectrum of Complications in Post Liver Transplant Patients: A Study of 30 Cases

Aftab Ahmed Siddiqui, Rakhshinda Jabeen, Moin Ahmed Ansari, Babar Bashir, Saeed Ahmed and Masoud Bakheet Khashoob.

Abstract
OBJECT: To study the complications encountered in post liver transplant patients performed
due to different etiologies leading to end stage liver disease.
STUDY DESIGN: Cohort and observational study.
PLACE AND DURATION OF STUDY: Sultan Qaboos University Hospital, Oman. From Dec 2001-
July 2006.
PATIENTS AND METHODS: The study was conducted on all patients having cadavaric liver
transplantation outside Oman. All patients were followed up for at least 18 months after enrolling
in the study. They all had certain routine tests at the start of the study and were repeated
according to the requirement of the individual patients. All patients had tacrolimus as an immunosuppressive
agent. Patients with hepatitis B had hepatitis B immunoglobulin, alongwith lamivudine
for relapse prophylaxis.
RESULTS: Complications of liver transplantation was observed in 21 patients, out of total 30
patients. Thirteen patients developed new onset diabetes mellitus, among them 7 had other
complications as well. Eight patients had different hepatic complications and 7 had non hepatic
problems. Total 5 patients expired during our follow up.
CONCLUSION: The complications of liver transplantation can be controlled and managed if diagnosed
promptly and treated early.

Key words: Cadavaric liver transplantation, End stage liver disease, Tacrolimus, Hepatic complications, Non- Hepatic complications.



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