Background: Fecal disimpaction is very important for successful management of constipation in children. Lactulose is cheap and wide available medicine in compare to other polyethylene glycol preparations. From our experience lactulose is effective and safe medicine for both disimpaction and maintenance therapy in constipated children.
Purpose: To evaluate the safety and efficacy of lactulose in fecal impaction management in children with constipation.
Methods: A prospective controlled trial conducted in children with functional constipation who presented with fecal impaction to Queen Rania Hospital for Children from 15 April 2018 until 15 October 2018. Two randomized matched groups; group A included 33 constipated children treated for disimpaction with higher dose lactulose (10gm/15 ml) 4-6 ml/kg/day (max. 120 ml/day), and group B included 32 children treated for disimpaction with macrogol (polyethylene glycol 4000) 1-1.5 gm/kg (max. 30 grams/day). Both groups received treatment until resolution or up to 6 days. Patients were followed over one week and success of disimpaction were observed, moreover, any adverse events were recorded.
Results: All patients in both groups achieved successful disimpaction by seventh day of therapy, group B showed significant faster response. Both therapies were tolerated and no significant adverse events were reported.
Conclusion: Both agents were safe, effective and well tolerated. lactulose may be a good alternative to polyethylene glycol in the treatment of fecal impaction in constipated children.
Lactulose; Disimpaction; Constipation; Children
Gripforce reduction in children with an upper neonatal brachial plexus lesions.
Buitenhuis SM, Pondaag W, Wolterbeek R, Malessy MJA
Journal of rehabilitation medicine. 2021; ():
Taijiquan and qigong as a mindfulness cognitive-behavioural based therapy on the treatment of cothymia in school-age children - A preliminary study.
Rodrigues JM, Lopes L, GonÃ§alves M, Machado JP
Journal of bodywork and movement therapies. 2021; 26(): 329-338
Hyperglycaemic hyperosmolar state in an obese prepubertal girl with type 2 diabetes: case report and critical approach to diagnosis and therapy.
Mohn A, Polidori N, Castorani V, Comegna L, Giannini C, Chiarelli F, Blasetti A
Italian journal of pediatrics. 2021; 47(1): 38
Portable HEPA filter air cleaner use during pregnancy and children's behavior problem scores: a secondary analysis of the UGAAR randomized controlled trial.
Enkhbat U, Gombojav E, Banzrai C, Batsukh S, Boldbaatar B, Enkhtuya E, Ochir C, Bellinger DC, Lanphear BP, McCandless LC, Allen RW
Environmental health : a global access science source. 2021; 20(1): 78
SODA MAPS: A Framework for Understanding Caffeinated Sugary Drink Consumption Among Children.
Halberg SE, Visek AJ, Blake EF, Essel KD, Sacheck J, Sylvetsky AC
Frontiers in nutrition. 2021; 8(): 640531