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Original Article

J App Pharm Sci. 2017; 7(1): 017-023


Quality evaluation of Dendrobium based on ultra-performance liquid chromatography (UPLC) and chemometrics

Caimei Gu, Xiang Zhang, Labin Wu, Xue Jiang, Linfang Huang.



Abstract
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Dendrobium is one of the most important herbs in the traditional Chinese medicine and widely distributed throughout Asia, Europe and Australia. Nowadays, the quality and safety of Dendrobium in usage among many different species are still big problems, while there are few reports illustrating it. In this study, 15 important species (60 samples) of Dendrobium were compared based on total polysaccharides, total alkaloids, dendrobine and bibenzyl using ultra-performance liquid chromatography (UPLC). The results showed that D. devonianum has the secondary top contents of polysaccharides and alkaloids among all the species, and erianin is detected only in D. chrysotoxum. This investigation provides scientific evidences for quality control and sustained development of Dendrobium plants.

Key words: Dendrobium; polysaccharides; alkaloids; UPLC; chemometrics







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