Background: The coronavirus disease 2019 (COVID-19) pandemic significantly impacted global health, with India experiencing one of the highest case and death tolls. However, data specific to India’s sociodemographic and clinical factors influencing COVID-19 mortality remains limited. Objective: This study aimed to identify sociodemographic and clinical factors associated with COVID-19 mortality in India. Methods: This retrospective, cross-sectional study analyzed medical records of 4961 adult COVID-19 patients admitted to a tertiary care center in North India, from April 2020 to December 2021. Sociodemographic and clinical data were captured using a structured proforma. Univariate analysis (chi-square test) and Kaplan-Meier survival analysis were performed to identify factors associated with mortality. Results: Of the 4961 patients, 557 (11.2%) died, and 4404 (88.8%) survived. Increased age, rural residency, professional occupation, and comorbidities (diabetes and hypertension), multimorbidity, increased disease severity, cold and flu symptoms, breathlessness, and the need for intensive care unit (ICU) admission and ventilator support were significantly (P
Key words: COVID-19; India; mortality; risk factors; comorbidity.
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