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Original Article

PAFMJ. 2016; 66(5): 738-741


A COMPARISON OF EQUIPOTENT DOSES OF TRAMADOL AND NALBUPHINE IN GYNECOLOGICAL LAPAROTOMIES POSTOPERATIVELY

Tanveer Hussain, Salman Ahmad, Arshad Taqi, Shahida Khwaja.

Abstract
Objective: To compare the mean consumption of equipotent doses of tramadol and nalbuphine for first 12 hours of post-operative analgesia, in patients undergoing gynaecological laparotomies.
Study Design: Randomized clinical trial.
Place and Durration of Study: Hameed Latif Hospital Lahore from 6 months.
Materials and Methods: One hundred American society of anaesthesiologists (ASA) I & II, consenting females, ages between 20 and 50 years were divided randomly into two equal groups. All patients were given a loading dose of either tramadol (1.5mg/kg) or nalbuphine (0.15mg/kg) after the induction of anesthesia. Same drug was continued as baseline infusion; tramadol 0.5mg/kg or nalbuphine 0.05mg/kg respectively was given as a bolus whenever the visual analogue scale (VAS) score was ≥3. Total dose given in bolus was calculated and compared. Time at the instant of first demand of analgesia in postop was also noted in both groups.
Results: Mean SD dose of rescue boluses in Tramadol group was 89.26 40.00 mg, while mean of equipotent dose of Nalbuphine group was 134.72 61.81 mg (p

Key words: Postoperative analgesia, nalbuphine, tramadol, VAS score.



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