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Original Article



Comparative study on the clinico-haemato-biochemical assessment of different anaesthetic agents in Rabbits

Rukhsana Amin Runa,Musfik Ahmed Firoz,Mst. Antora Akter,Md. Mahmudul Alam.



Abstract
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Aim: The study aimed to compare the effects of different anaesthetics on physical and haemato-biochemical parameters associated with reflexes in rabbits.
Methods: Fifteen healthy rabbits (1.5-2.0 kg) were randomly allocated into three groups: Group XK (Xylazine- Ketamine), Group MK (Midazolam- Ketamine), and Group MCK (Midazolam- Chlorpromazine- Ketamine). The rabbits were given specific doses of ketamine (20 mg/kg), midazolam (0.5 mg/kg), and xylazine (2 mg/kg) intramuscularly. The physical parameters of heart rate, respiration rate, and rectal temperature, as well as the reflexes of righting, palpebral, and pedal, were assessed before administering anaesthesia and at 10, 20, 30, 40, 50, 60, 70, 80, 90, and 100 minutes following the injection of various anaesthetics.
Results: Rectal temperature significantly differed throughout the anaesthetic period in the animals of group MK and group MCK. The heart rate and respiration rate exhibited substantial alterations (P

Key words: Anaesthetics, physical parameters, reflexes, serum biochemistry, rabbits







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040506070809101112
2025

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