Abstract

Objective: To study Multiorgan pathophysiology of endometriosis by evaluating Neurotrophin linked Multifaceted Health Risks Assessments.
Methodology: This research analyzed 60 participants using a case-control design, including 40 endometriosis patients (mean age: 35.4±6.2 years) and 20 healthy controls (mean age: 34.8±5.9 years). This collaborative research was conducted from March to June 2023 mainly at Shaikh Zayd Hospital Lahore. We obtained samples of endometrial biopsies together with peritoneal fluid and plasma. The analysis quantified BDNF gene expression from extracted RNA through qRT-PCR testing of GAPDH as the reference gene. Clinical investigators obtained pain scores from the VAS scale and recorded rAFS classification scores for lesion severity. The statistical analysis contained both ΔΔCt calculations and a correlation analysis. p

Key words: BDNF, endometriosis, metabolic disorder, multi-system disorder.,