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Original Article

PAFMJ. 2016; 66(4): 490-493


CYTOLOGICAL GRADING OF BREAST CANCER ACCORDING TO ROBINSONíS GRADING SYSTEM

Rubina Younis, Iqbal Muhammad, Alia Zubair, Shahzad Azam, Aiza Saadia.

Abstract
Objective: To see the correlation between cytological parameters and grading of breast cancer according to Robinsonís grading system on Fine needle aspiration smears. Study design: It was a correlational descriptive study.
Study Design: It was a corelational descriptive study.
Place and Duration of Study: It was conducted in the Histopathology Department, Army Medical College, National University of Sciences and Technology (NUST), Rawalpindi, Pakistan from Nov 2012 to Nov 2013.
Material and Methods: All cases diagnosed as breast cancer (C 5) or suspicious of breast cancer (C 4), on Fine needle aspiration cytology, were included in the study and women already taking treatment were excluded. A total of 102 samples were included in the study through non probability convenience sampling.
Result: The cytological parameters of Robinsonís grading system including cell dissociation, nuclear margins and nuclear chromatin showed weak correlation with tumor grade. While cell size, cell uniformity and nucleoli showed moderate correlation. All the parameters were statistically significant with p-value

Key words: Anaplasia, Breast, Carcinoma, Chromatin, Ductal, Fine- Needle Aspiration, Pakistan.



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