Home|Journals|Articles by Year|Audio Abstracts
 

Case Report

PBS. 2016; 6(4): 230-3


Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease

Shazia Farheen Qureshi, Javed Ather Siddiqui, Yousef Bin Ahmed Shawosh.




Abstract

We report the case of a 20 year old unmarried female patient who has been diagnosed as schizophrenia with intellectual disability. Patient was on chlorpromazine since last three years subsequently develop hyperprolactinemia, later manifested into fibrocystic breast disease. Hyperprolactinemia, is known for decades as neglected side effect of antipsychotic medication. Prolactin is secreted in a pulsatile manner by the anterior pituitary gland. The main physiological function of prolactin is to cause breast enlargement and galactorrhea initially and later develop to fibrocystic breast disease. Routine investigation also revealed hypothyroidism. Prolactin is known as immunomodulator, and has been linked to benign or malignant tumor growth.

Key words: hyperprolactinemia, hypothyroidism, chlorpromazine, fibrocystic breast disease






Full-text options


Share this Article


Online Article Submission
• ejmanager.com




ejPort - eJManager.com
Refer & Earn
JournalList
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.