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Original Article

IMJ. 2017; 9(1): 24-28


FREQUENCY OF METABOLIC SYNDROME AND ASSOCIATED MORTALITY IN NEWLY DIAGNOSED ACUTE ISCHEMIC CARDIAC PATIENTS.

JAHANZEB MAQSOOD, ADNAN GHAFOOR, TALAL SAFDAR.

Abstract
OBJECTIVES: To determine the frequency of metabolic syndrome in acute ischemic cardiac patients and its impact on hospital outcomes.
STUDY DESIGN: Descriptive case series study.
Place and Duration: Coronary Care Unit (CCU), Fauji Foundation Hospital, Rawalpindi over a period of nine months i.e. from 18th Feb 2011 to 18th Nov 2011,
METHODOLOGY: A total of 188 patients were admitted with first ever episode of acute ST elevated myocardial infarction (diagnosed on the basis of WHO Criteria for diagnosis of acute MI). Outcomes measured were frequency of metabolic syndrome, median duration of hospital stay, the development of clinical heart failure (classified as per Killip classification) and in-hospital case mortality.
RESULTS: Among the 188 patients, 76% fulfilled the National Cholesterol Education Program ATP III criteria for metabolic syndrome. The median duration of hospital stay was five days. Increased incidence of heart failure and increased mortality was observed among patient with metabolic syndrome
CONCLUSIONS: The frequency of metabolic syndrome in acute ischemic cardiac patients was high and was found to be associated with adverse hospital outcomes, with a higher risk of development of heart failure and mortality.

Key words: Metabolic syndrome, coronary artery disease, acute myocardial infarction, hospital outcomes, insulin resistance, syndrome X.


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