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Natl J Med Res. 2012; 2(3): 366-368

Screening for Hemoglobinopathies in blood donors from Eastern Uttar Pradesh, India.

V K Meena, Kailash Kumar, L P Meena, Anju Bharti, A Kumar.

Abstract :
Objectives :Study the prevalence of hemoglobinopathies in blood donors from eastern U. P. India.
Materials and Methods : 1200 non-remunerated blood donors, between 18-40 years age, included in study. Both replacement and voluntary healthy blood donors included in the study. Blood Donor Selection criteria used as prescribed AABB Technical Mannual. Screening for thalassaemia was done by using D-10, Bio Rad, based on High Performance Liquid Chromatography (HPLC) .
Results : Among the 1200 blood donors 19 (1.58%) found positive for -thalassemia. Out of these 19, -thalassemia trait was most common (63.15%). In all donors blood groups, B + was commonest (44.08 %),but among the -thalassemia trait A + blood group was most common (33.33 %) .
Conclusion : Screening for thalassemia trait should be included as part of a standard blood testing before blood donation and a national policy must be formulated to screen the blood used for transfusion. However, this needs further studies to look at red cell kinetic studies and the effects of donated thalassemic blood in transfused patient.

Key words: Effect of HAART, HIV and hypogonadism, Male HIV

Key words: Key words: Effect of HAART, HIV and hypogonadism, Male HIV

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