Abstract

The case report details a 65-year-old female patient hospitalized at a tertiary care teaching hospital in South Karachi, who developed acute thrombocytopenia after initiating low-dose aspirin for cardiovascular prevention. Laboratory tests revealed a platelet count of 30,000/μL, along with abnormal liver function tests, coagulation factors, and renal function parameters. The patient received conservative management and her platelet count returned to normal after discontinuing aspirin. This case highlights the importance of identifying aspirin as a potential cause of thrombocytopenia and the need for a comprehensive differential diagnosis, particularly in patients with preexisting gastrointestinal conditions.

Key words: Aspirin-induced thrombocytopenia, celiac disease, chronic liver dysfunction, hematological abnormalities, coagulopathy.