Home|Journals|Articles by Year Follow on Twitter

Directory for Medical Articles

Open Access

Original Research

Pharmacological evaluation of cytoprotective potential of Phyllanthus Emblica (PE) and Asparagus Racemosus (AR) in preventing gastric erosions, ulcerations and inflammation induced in rats

Shirish Joshi, Urmila Thatte.

Cited by (1)

Background: Most of the currently available therapies for peptic ulcer disease have their own limitations and an ideal therapeutic agent is not yet available in the market.Hence,we decided to explore the cytoprotective potential of Indian Medicinal Plants namely Phyllanthus emblica and Asparagus racemosus along with ranitidine as a positive control in various animal models.

Aims & Objective: To evaluate the cytoprotective effect of the extracts of Phyllanthus emblica (PE) and Asparagus racemosus (AR) in preventing gastric erosions, ulcerations and inflammation induced in rats.

Materials and Methods: Cold immobilization stress, ethanol (99.9%), aspirin were the experimental models selected for inducing gastric erosions and ulcerations. Ulcer index , erosions, oedema, congestion and inflammation were the parameters studied for assessing gastric damage whereas carrageenininduced rat paw oedema model was used to induce inflammation.Ranitidine was used as a positive control.

Results: The two drugs chosen for the study namely Phyllanthus emblica and Asparagus racemosus prevented gastric damage significantly in the ethanol group (p

Key words: Ulcer Index, Inflammation, Paw Oedema

Similar Articles

Research advances on how metformin improves memory impairment in "chemobrain".
Alhowail A, Chigurupati S
Neural regeneration research. 2022; 17(1): 15-19

Neutrophil DREAM promotes neutrophil recruitment in vascular inflammation.
Li J, Kumari T, Barazia A, Jha V, Jeong SY, Olson A, Kim M, Lee BK, Manickam V, Song Z, Clemens R, Razani B, Kim J, Dinauer MC, Cho J
The Journal of experimental medicine. 2022; 219(1):

HOTTIP downregulation reduces neuronal damage and microglial activation in Parkinson's disease cell and mouse models.
Lun P, Ji T, Wan DH, Liu X, Chen XD, Yu S, Sun P
Neural regeneration research. 2022; 17(4): 887-897

Dying by fire: noncanonical functions of autophagy proteins in neuroinflammation and neurodegeneration.
Rickman AD, Hilyard A, Heckmann BL
Neural regeneration research. 2022; 17(2): 246-250

Neutrophil-to-lymphocyte ratio in sporadic amyotrophic lateral sclerosis.
Wei QQ, Hou YB, Zhang LY, Ou RW, Cao B, Chen YP, Shang HF
Neural regeneration research. 2022; 17(4): 875-880

Full-text options

Latest Statistics about COVID-19
• pubstat.org

Add your Article(s) to Indexes
• citeindex.org

Covid-19 Trends and Statistics
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.

ScopeMed Web Sites