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J App Pharm Sci. 2016; 6(12): 197-201


Triterpenes from Pouteria gardneri (Mart. & Miq.) Baehni extracts

Cintia Alves de Matos Silva, Ricardo de Oliveira e Melo, Inês Sabioni Resck, Dâmaris Silveira.




Abstract

Pouteria gardneri (Sapotaceae) is a South America native species found in Bolivia, Paraguay, and Brazil. Local inhabitants appreciate the edible fruits (“sapotinha”). In Brazil, this species grows in almost all biomes, including the Cerrado. However, there are few studies about this plant. In a phytochemical study of leaves of P. gardneri, the triterpenes delta-amyrin, alpha- and beta-amyrin acetate, lupeol acetate, taraxasterol acetate were characterized in hexane extract, by GC-MS and 1H and 13C NMR analysis. Further column chromatography separation led to the isolation of alpha-amyrin acetate. Ethanol crude extract was submitted to a triphase liquid-liquid partition. From silica gel column of MeCN-CHCl3 fraction, a mixture of oleanolic and ursolic acid was obtained. All isolated substances were characterized by 1H and 13C spectra data, in comparison to literature. As far we know, it is the first time the chemistry composition of Pouteria gardneri is investigated.

Key words: Pouteria gardneri, Sapotaceae, Cerrado, medicinal plant






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