This study evaluates motor in coordination effects of eugenol by using the respective animal models. Though a few isolated studies to evaluate analgesic, anticonvulsant, antinociceptive and sedative effect of eugenol were done earlier, there was no single study like this one that tested a gamut of motor in coordination effects in a single study with pure eugenol. This study shows eugenol has mild motor co-ordination activity in restraint stress-induced animal models at the dose of 150mg/kg.b.wt. However, this could be possible due to the antistressor and antioxidant activity of eugenol. Further studies are required to explain precise mechanisms implicated in such a varied response at wider range of doses and dosage combinations and to elucidate potential therapeutic utility of eugenol.
Key words: Eugenol, Wistar albino rats, Immobilization stress, Rota rod, Stair case,
Narrow beam.
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