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PHYLLODES TUMOR OF THE BREAST : A CLINICOPATHOLOGICAL ANALYSIS FROM A SINGLE INSTITUTION

Naoual Benhmidou, Fadoua Rais, Fadila Kouhen, Abdelhak Maghous, Hasna Loughlimi, Khadija Bellahammou, Hanan Elkacemi, Tayeb Kebdani, Sanaa Elmajjaoui, Noureddine Benjaafar.


Abstract

The aim of our study is to examine the clinical and pathological features of patients with breast phyllodes tumors and to determine features that are correlated to outcome. Forty four phyllodes tumors were assessed. There were 11 benign, 11 borderline and 22 malignant tumors. 10 of 44 patients (22.72 %) relapsed at any site. Seven patients (15.9 %) had a local recurrence and 3 patients experienced local and metastatic relapse. The 5-year and 10-year survival rates are 97% and 95 % respectively. The 5 years and 10 years DFS are 81% and 77% respectively. Grade, histological size, margin involvement impacted disease free survival. Adjuvant radiation therapy improved local control in high grade tumors although it didn’t reach significance.

Key words: Phyllodes tumors, recurrence, prognostic factors






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